Genetic and phenotypic differentiation of an Andean intermediate altitude population
نویسندگان
چکیده
منابع مشابه
Genetic and phenotypic differentiation of an Andean intermediate altitude population
Highland populations living permanently under hypobaric hypoxia have been subject of extensive research because of the relevance of their physiological adaptations for the understanding of human health and disease. In this context, what is considered high altitude is a matter of interpretation and while the adaptive processes at high altitude (above 3000 m) are well documented, the effects of m...
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BACKGROUND AND OBJECTIVES Millions of people live above an altitude of 2,500 m and are at risk of chronic mountain sickness (CMS), a disorder of excessive red cell and hemoglobin production. Preferential ethnic backgrounds, familial character, and heritability studies have suggested that genetic factors make a major contribution to the pathogenesis of CMS, thus our goals were to exploit a proba...
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We compared the spirometric values of people living at High Altitude at the Andean Plateau with those predicted for lowland population. RATIONALE Spirometry reference values are not yet available for the millions of people living at high altitude in the Andean High Plateau. OBJECTIVE To obtain spirometric prediction equations from a healthy subset of adults living in Argentina at 3440m abov...
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Selenium (Se) levels in blood (whole blood, erythrocytes and serum) and blood glutathione peroxidase (GSH-Px) activity were investigated in people living at high altitude in Bolivia (4,000 m above sea level). These parameters were compared to those of people living at low altitude (300 m above sea level). The Se levels in whole blood of the high-altitude subjects did not differ significantly fr...
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The ability to succeed in diverse conditions is a key factor allowing introduced species to successfully invade and spread across new areas. Two non-exclusive factors have been suggested to promote this ability: adaptive phenotypic plasticity of individuals, and the evolution of locally adapted populations in the new range. We investigated these individual and population-level factors in Polygo...
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ژورنال
عنوان ژورنال: Physiological Reports
سال: 2015
ISSN: 2051-817X
DOI: 10.14814/phy2.12376